From: GEVANS613-AT-aol.com
Date: Tue, 8 Jun 2004 17:52:01 EDT
Subject: Hope of  New Cure for Heideggeronism?


1: J Neurol Neurosurg Psychiatry.  2004  Apr;75(4):640-2.

Religiosity is associated with hippocampal but not  amygdala volumes in
patients with refractory epilepsy.

Wuerfel J,  Krishnamoorthy ES, Brown RJ, Lemieux L, Koepp M, Tebartz van Elst
L, Trimble  MR.

Raymond Way Neuropsychiatry Research Group, University Department  of
Clinical Neurology, Institute of Neurology, Queen Square, London,  UK.

OBJECTIVE: To assess the relationship between the behavioural triad  of
hyper-religiosity, hypergraphia,heideggeronism, and hyposexuality in  
epilepsy, and volumes
of the mesial temporal structures. METHOD: Magnetic  resonance images were
obtained from 33 patients with refractory epilepsy and  mesial temporal 
structure
volumes assessed. Amygdala and hippocampal volumes  were then compared in 
high 
and low scorers on the religiosity, writing, and sexuality sub-scales of  the 
Neurobehavioural Inventory. 
RESULTS: Patients with high ratings on the
religiosity scale had  significantly smaller right hippocampi. Religiosity
scores rated by both  patient and carer showed a significant negative 
correlation
with right  hippocampal volumes in this group. There were no other 
differences  in
amygdala or hippocampal volumes between these groups, or between high  and
low scorers on the writing and sexuality sub-scales. CONCLUSIONS: These  
findings
suggest that right hippocampal volumes are negatively correlated  with
religiosity in patients with refractory epilepsy.

PMID: 15026516  [PubMed - indexed for  MEDLINE]
=============================================================================1:  Epilepsy Behav.  2003 Jun;4(3):291-7.

Psychopathological profile in  patients with severe bilateral hippocampal
atrophy and temporal lobe  epilepsy: evidence in support of the Geschwind 
syndrome?

van Elst LT,  Krishnamoorthy ES, Baumer D, Selai C, von Gunten A, Gene-Cos N,
Ebert D,  Trimble MR.

Institute of Neurology, University College, Queen Square,  London WC1N 3BG,
UK.

Bilateral symmetrical hippocampal atrophy (BHA)  has been implicated as a
possible causal element in various neuropsychiatric  disorders, in particular
depressive disorder and schizophrenia. To test the  hypothesis that bilateral
symmetrical severe volume loss of the hippocampi is  of causal relevance to
these psychiatric syndromes rather than an  epiphenomenon we assessed the
psychopathology in a group of patients with  temporal lobe epilepsy (TLE) and
very severe bilateral symmetrical  hippocampal atrophy and compared it with
that of a patient control group.  Patients with TLE and hippocampal volumes
smaller than three standard  deviations below the mean of a control 
population were identified and compared  with a matched patient population with normal
hippocampal volumes.  Psychopathology was assessed by blinded trained
psychiatrists using the  Present State Examination and Neurobehavioral
Inventory. The prevalence of  psychiatric syndromes was high in both patient 
groups; however, there was no  significant difference between the two groups. 
With use of the more specific  Neurobehavioral Inventory a psychopathological 
pattern reminiscent of the  Geschwind syndrome emerged when patients with BHA 
were characterized by  caregivers. While BHA does not result in an increased
prevalence of specific  psychiatric syndromes, specific symptoms that
characterize the Geschwind  syndrome like hypergraphia and hyposexuality
might be pathogenically related  to hippocampal atrophy.

PMID: 12791331 [PubMed - indexed for  MEDLINE]


Nullius in Verba

_http://evans-experientialism.freewebspace.com/index.htm_ 
(http://evans-experientialism.freewebspace.com/index.htm) 
JUD  EVANS - XVANS XPERIENTIALISM



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